Release date: 2014-03-18
It was learned from Donghua University that the research group of Professor Zhang Yanzhong of the Institute of Bioscience and Technology of the University used electrospinning technology combined with a new shape memory polymer to develop a tissue engineering bionic stent with shape memory effect.
Related research results were published in the American Chemical Society - Applied Materials and Interface. The American Chemical Society weekly "Chemical and Chemical News" also reported on this.
Fractures are common orthopedic injuries. About 10% of the injured patients will have bone nail holes on the bones due to fracture healing. How to reduce the incidence of re-fracture and "reinforce" the mechanical defects of bone?
To this end, Zhang Yanzhong's research group began research on bone repair biomaterials in 2002. The newly developed tissue engineering bionic scaffold not only has the structural characteristics of bionic natural bone nanofibers, but also promotes the osteogenic properties of bone cell growth, and can recover shape memory under the action of body temperature, tightly fill the defect of the nail and reduce the fracture. gap. At the same time, the stent has biodegradable properties, which is better compatible with the original bone tissue, and does not need to be taken out again, thereby achieving the purpose of regenerating bone tissue in situ.
Zhang Yanzhong said that the team will conduct in-vivo experiments to further verify the actual efficacy of the new bone-implanted stent in repairing bone defects in vivo. It is reported that the team has already conducted in-depth cooperation with experts from Zhejiang University and Shanghai First People's Hospital.
Source: China Medical Technology Network
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