Release date: 2014-12-01
Researchers at Tufts University in the United States worked with a team at the University of Illinois at Urbana-Champaign to develop a project and showcase the results to the public. The project they jointly developed is an electronic implant that is triggered by a remote wireless signal to eliminate bacterial infections in mice and to be absorbed by heating. This device made of silk and magnesium can be dissolved in the tested mice. This technique was previously only shown in test tube experiments. This paper has been published in the journal of the National Academy of Sciences.
Experts in biomedical engineering and professors at these schools believe that this technology is an important demonstration of the continued advancement of medical devices. This technology can perform corresponding therapeutic functions on patients through remote start-up, and can be safely after treatment is completed. Disappeared, no need to retrieve it. This treatment can help doctors better control the infection after surgery, and this way allows doctors to control the patient's "drug" dose in a wireless form.
Implantable medical devices are not uncommon, and have long been widely used. However, in the past we usually used non-degradable materials. Due to the limited service life of these devices, we still need to remove or replace the device from the body. The new wireless treatment device can be treated differently according to the doctor's treatment of silk protein to achieve harmless dissolution after a few minutes or weeks.
Each fully soluble wireless heating device consists of a meandering resistor and a coil of electrical power that is placed on the silk protein layer. The magnesium heater is housed in a silky "pocket" that protects the electronics and controls its dissolution time.
The device was implanted in living tissue of a rat infected with S. aureus, then activated by a wireless transmitter and subjected to two sets of 10 minutes of heat treatment. The devices in the tissue collected data on the mice 24 hours after treatment. The data indicated that there were no signs of viral infection in the mice, and the surrounding tissues were also considered normal. The device was completely dissolved after 15 days, and the magnesium content was at the same level as the magnesium content in the usual human body at the implantation site and the surrounding area.
Researchers are currently conducting other in vitro experiments, and if the experiment is mature, the implantable device can be added to treat more diseases. This wirelessly controlled device can also play a significant role in the treatment of diseases associated with infections that are likely to cause infection by increasing the release of antibiotics without reducing the activity of the antibiotic.
Source: Lei Feng Net
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