Release date: 2016-02-22
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On an ordinary working day, in an inconspicuous unit building in Huilongguan, Li Shao and her friends started a busy day of work early, and this state has lasted for two years. Li is the founder of Beijing Yaguo Technology Co., Ltd. (hereinafter referred to as “Yaguo Technologyâ€), an innovative medical device company specializing in airway management and respiratory therapy, and is working on a critically ill patient worldwide. "The most advanced and most user-friendly" auxiliary drainage system.
Doing medical equipment is a very "heavy" thing, to be able to withstand loneliness and withstand the pressure. Yaguo Technology has been very low-key for two years. Although I have achieved very good results in the entrepreneurial competition, I have never been interviewed, and I have always maintained the passion of the early stage of entrepreneurship and the pace of my work. Li Shiao said that he should be motivated until he completes the clinical. “Whether research and development, factory construction, clinical or financing, it is like the process of deciduous teeth when you are a child: the rhythm can only be grasped by yourself. Sometimes you have to slap it down yourself, sometimes you have to wait patiently until it falls.†Now, The intelligent biomimetic drainage system developed by the company has entered the clinical trial stage. It is expected that it will be officially entered the market through medical device certification within 2016. Li said, "It is time for everyone to know us."
Help patients "cough" like normal people
The driving force of other industries comes from the pursuit of fun or fun. The driving force of the medical industry often comes from pain.
"My father was a victim of a shortage of medical devices in the 1990s." Li said the arterial network. "His illness should have been diagnosed with CT, but the hospital does not have a CT. It can only be guessed. The result is unfortunately guessed. Later, I looked at his diary and felt very sad. The doctors are not gods, but they are facing the most sacred life, so they need powerful tools." Li Shao has entered the medical device industry since the beginning of his studies. "I am fortunate to have made both of the two devices that I have mastered." The reason for doing bionic sputum drainage equipment comes from the experience of a friend taking care of a relative in the ICU: "It is too painful to suck and watch." This friend took out the seed money of Yaguo.
"Life has only two endings, intubation or no intubation." In China, 625,000 ventilators are in use every year, and they are still increasing at a rate of 10% per year, of which invasive ventilators account for 58.3%. The most common and fatal complication of using an invasive ventilator is ventilator-associated pneumonia, with an incidence of 43.1% and a case fatality rate of 51.6%. The main reason is that patients cannot effectively discharge secretions. There are three methods (devices) for clinically solving this problem.
The first method is to drain through the suction tube. This method requires professional nurse operations. This method is tantamount to a nightmare for the patient. The process of sucking the tube down to the airway is very painful, and each patient has several intubation and drainage every day. In addition, this method can only clean the main airway, there is no way to clean the secretions in the bronchi, and the drainage effect is not good. This is the most common method currently used.
The second method is to vent the sputum through the vibrating shovel. Before the clinical use of nurses to shoot back the sputum drainage, the working mechanism of the vibration sputum machine is to replace the nurse's back with mechanical vibration. The clinical effect of this method is not very satisfactory, and the vibration also acts on the arm of the operating nurse, causing fatigue.
The third method is mechanical airway vacuum suction. At present, there is a device on the market. During use, the ventilator needs to be removed, and the positive pressure of the device itself is used to deliver air to the lungs, and then the negative pressure is used to suck out the gas in the lungs. The biggest problem with this method is that it is cumbersome and dangerous. It can't be achieved in critically ill patients, and it can cause lung damage in patients. It is rarely used in ICU.
Yaguo Technology's intelligent bionic drainage system simulates a person's normal cough from both airflow and muscle movement, enabling patients to safely and efficiently remove the deep lung secretions like a normal person through coughing. Previously, there was no such bionic sputum product on the market, and this system could fill a gap in the medical device market segment.
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The system works with the ventilator. After the ventilator helps the patient inhale, the sensor of the Yaguo product determines whether the inspiratory process has ended. When the inhalation process is over, the patient is assisted in exhaling. In addition, the intelligent bionic drainage system utilizes external electrical stimulation to allow the main respiratory muscles to act accordingly, assist with drainage, and contribute to the recovery of the patient's respiratory function.
Moreover, this system has only a gas path link with the ventilator, does not produce other connections, and can be used with any type of ventilator, which is conducive to cooperation with ventilator manufacturers to open up the market.
Li said that the biggest advantage of this system is that patients have a safe, efficient and easy drainage experience.
In addition, the system includes a network acquisition and big data analysis module that monitors and manages the user's sputum status in real time, and can then use big data to guide medical procedures and offline catheters.
Yaguo's first product is cut from the most difficult place, aiming at the life and death of critically ill patients. On this basis, it will be familiar with the development of general wards and family products. Li said that in the future, system mainframes and consumables will be their main profit points. It is estimated that there are tens of billions of domestic markets and hundreds of billions of international markets.
Angels along the way
Angel investors are Yu Rong, Chairman of the Board of Directors of Mei Nian Health, and Li Wenzhao, Managing Director of Zhongwei Fund.
In the process of starting a business, Li Xiao was fortunate that the angel investor not only gave her team great support in funding, but also had the same philosophy with them: this project is very valuable and more meaningful, regardless of success or failure. We are also doing something meaningful together.
When Li Shiao first met Yu Rong, the chairman of the US Health Center, Yu Rong said to her, "This thing can help a lot of people, I support you."
When Li Wenzhao, the managing director of Zhongwei Fund, knew about Li Shao, she just resigned from a research and development position of a well-known medical device company in China. After a brief contact, Li Shao’s sincerity and seriousness deeply touched him.
At the 2015 Sci-tech University China Campus Recruitment Competition, Li Wenzhao said such a paragraph to evaluate Yaguo Technology, “
As a former doctor, when a project can save patients from the chronic illness with a mortality rate of 52%; in addition to supporting it, I don't know what other options?
As an investor focused on medical care, when you meet an entrepreneur and put all your dreams and passions into a life-saving career; in addition to supporting her, I don't know what choices are there?
Whenever a relative of a patient who has experienced death and death, sees a product that can relieve pain, restore health, and prolong life for relatives on the sickbed; I support her except now, I don't know what else can we do?
Team and honor
At present, Beijing Yaguo Technology Co., Ltd. has a total of more than 900 square meters of office space, laboratory and clean workshop. “There is a multidisciplinary, multi-year technically accumulated team behind this innovative medical device.†Yaguo's engineers span the 60s, 70s, and 80s. It is really a team of old and young. Most of the company members come from the Chinese Academy of Sciences, Tsinghua University, or Xueba, or a senior engineer from a leading company in the industry. At the same time, the team has a number of medical consultants from the top three hospitals, including the attending physician and department head, as well as expert consultants from the Chinese Academy of Sciences who enjoy special allowances from the State Council.
The company has applied for more than a dozen patents, seven have been authorized, and the rest are at different stages of trial.
In the road show of the Black Horse Games in April 2015, Yaguo Technology won the championship. In May of the same year, as the most innovative enterprise representative in China, Yaguo participated in the China Student Recruitment Competition sponsored by Baidu News by Singular University. After fierce competition, Yaguo became the only elected representative in China and visited the United States. Silicon Valley has joined the world's top creative corporate clubs and has been among the most pioneering entrepreneurs in the world. Li Shao was also associated with Google X. They visited this inconspicuous unit twice and asked Yaguo to apply for their Solve for X project. The final intelligent bionics system was approved and selected as a moonshot, becoming one of the five moonshots presented at the first Asian conference in Solve for X in November 2015. In the same year, Yaguo won the Excellence Award in the final of the China Innovation and Entrepreneurship Competition.
Financing plan
At present, Yaguo has launched a new round of financing, and the funds will be used for production and construction, marketing and product development. Li said, "As the environment worsens and the aging is intensifying, more and more patients need invasive ventilation, and airway management as a part of the survival rate must be upgraded. From mechanical to intelligent bionics, this upgrade is just a need, and it is a very big step forward. It will open a new era of airway management for critically ill patients."
Source: Arterial Network
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