New treatments that can treat all food allergies
November 11, 2016 Source: Omelette Net
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];In the best case, food allergies are just the most frustrating thing, but in the worst case it can even be life-threatening. But scientists have developed an immune technology that can completely transform allergic reactions in mice, which they believe can be used to treat allergies in humans.
This treatment works by triggering the body to produce new dendritic cells that send signals to other immune cells, eliminating their hyperimmune response. This ensures that the most rapid and severe anaphylactic shock no longer occurs.
John Gordon, a lead scientist at the University of Saskatchewan in Canada, said: "If we can really cure food allergies or related diseases, such as asthma and autoimmune diseases (multiple sclerosis, etc.), then this treatment will change the affected individual. life."
Dendritic cells naturally appear in tissues that are connected to the external environment, such as the outer skin of your body and the lining of the nose, lungs, stomach, and intestines.
Gordon and his team extracted the cells from the mice and exposed them to a special protein mixture. The vitamin A-related acids naturally exist in the human gut and allergens such as peanuts and egg whites.
When the modified dendritic cells were reintroduced into the mice, the allergic reactions in them were almost eliminated. Sensitive immune cells that were originally activated by allergens behave as if they were present in healthy, non-allergic individuals.
Although this technology has only been tested on mice so far, the researchers hope to apply it to human trials in the next few years.
Gordon said: "Many people with allergies volunteer to provide the cells in their body so that we can study in the laboratory to further advance this technology."
Effective ways to treat allergies can change the lives of millions of people. In the United States alone, food allergies affect approximately 15 million people, and one out of every 13 children is allergic to something.
The team believes that their research can also be applied to other diseases associated with the immune system, such as multiple sclerosis.
Gordon explained: "You only need to change this therapy a little, it can be used to treat autoimmune diseases."
The study has been published in the Journal of Allergy and Clinical Immunology.
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