On May 30, 2018, the first needle and nine-valent HPV vaccine in the inland area was injected at the Boao Super Hospital and the Yijia Medical Center in Hainan. Subsequently, cities such as Hangzhou, Shenzhen and Guangzhou began to accept appointments for the nine-valent vaccine. A few days ago, according to relevant media reports, some grassroots inoculation sites in Beijing have been open to book a nine-price cervical cancer vaccine, and private hospitals have revealed that many citizens have already made an appointment for injection.
Pang Xinghuo, deputy director of Beijing CDC, said: Beijing's nine-price cervical cancer vaccine has completed the bidding procurement work, and has started the vaccination appointment. Now the vaccine has arrived, and women of the appropriate age (the nine-priced HPV vaccine is suitable for women aged 16 to 26) There is such a need, you can make a reservation vaccination at the inoculation point, complete three vaccination procedures, inoculated in 0, 2 months, 6 months, all 3 doses should be completed within 1 year.
In terms of price, compared with cities such as Hangzhou, Shenzhen and Guangzhou, the price of inoculation in Beijing is similar. The bidding price is 1298 yuan, plus the second-class vaccine injection fee of 25 yuan, totaling 1,323 yuan per needle, three needles. A total of 3,969 yuan, and the price of a single vaccine in Shenzhen and Guangzhou is also 1,323 yuan, a total of 3,969 yuan for three needles, a price of 1,326 yuan for Hangzhou, and 3,978 yuan for three needles. At the same time, some private medical treatments in Beijing can also accept appointments. The total price of the three needles ranges from 5,800 yuan to 5,980 yuan.
At present, Beijing's appointments have been very popular. In Hangzhou, Shenzhen, Guangzhou and other cities that have previously opened appointments, the nine-valent cervical cancer vaccine is even more difficult.
In Guangzhou, according to the vaccination clinic doctors at the Rainbow Street Community Health Service Center in Liwan District, the number of nine-valent vaccines currently arriving at the social security centers in the district is limited. The current practice of the center is to give priority to the residents or permanent residences of the street. Women are vaccinated in the district's jurisdiction and online appointments are not open.
In Shenzhen, on August 16, the first needle of Shenzhen nine-valent cervical cancer vaccine was opened in the adult vaccination clinic of Luohu Hospital. According to media reports, according to Wang Wuxin, the inoculation director of the hospital, after the official opening of the appointment at 12 noon, Shenzhen The nine-valent cervical cancer vaccination appointment has been scheduled for November 30, and all 1060 places have been filled.
In Hangzhou, according to the staff of the Hubin Street Community Health Service Center in Shangcheng District of Hangzhou, due to the large number of appointments, the registration appointment has been suspended. “Up to dozens of people can be called. The number of registered appointments is several times the quantity available. ."
As the world's first vaccine for the prevention of cancer, the market for cervical cancer vaccine has been receiving much attention. At present, cervical cancer vaccines on the market have two, four and nine prices, and all have entered China, especially the nine-price. Vaccine, because it can prevent a variety of subtypes, has been favored and concerned by consumers, and many companies in China are also rushing to the nine-price market. Up to now, including Xiamen Wantai Bohai Biotechnology Co., Ltd., Shanghai Bowei Biotechnology Co., Ltd. The company and Shanghai Zerun Biotechnology Co., Ltd. have approved the clinical trial of the nine-valent cervical cancer vaccine for three drugs. It has been estimated by industry insiders that according to the current CDE approval rate for imported drugs and domestically developed new drugs, the latest is In 2019, the domestic nine-priced HPV vaccine will be ushered in for approval and listing to enrich the Chinese market.
Luo Jianhui, director of the Department of Biological Products and Pharmacy of the National Center for Drug Evaluation, also said that it is expected that more and more HPV vaccines will be available for public selection in the next few years. The time for the listing of specific domestic vaccines depends on the speed of research and development of enterprises, and the Drug Evaluation Center strengthens. Communicate with the company on R&D declarations, consider whether there is any further time-saving, and change the previous series to the parallel optimization method to jointly promote the technical requirements for the vaccine to reach the market as soon as possible.
HPV Vaccination Tips:
What is the difference between the price of two, four, and nine?
A bivalent vaccine can prevent infections caused by HPV16 and HPV18 viruses. According to international research data, more than 70% of cervical cancers are caused by these two viruses.
The tetravalent vaccine can prevent HPV6, 11, 16, and 18 virus infections. Although HPV6 and HPV11 are not classified as high-risk HPV viruses for cervical cancer, they can cause lower genital warts.
The nine-valent vaccine is aimed at nine subtypes of HPV 6, 11, 16, 18, 31, 33, 45, 52, and 58. Studies have shown that a nine-valent vaccine can prevent 90% of cervical cancer.
It should be pointed out that HPV vaccine can not prevent cervical cancer 100%, even after vaccination, regular cervical cancer screening.
What is the difference between the three vaccination ages?
From the age of vaccination, the age of vaccination approved in China is two, for two women aged 9 to 45, four for women aged 20 to 45, and nine for women aged 16 to 26.
The age segmentation is based on domestic clinical trial data for different age groups. The HPV vaccine is a preventive vaccine, and no results have been shown to have a disease-preventing effect on people who have already been infected with the HPV-type virus contained in the vaccine. Therefore, the population before the sexual exposure has the best health economic efficiency.
In the position paper updated by the WHO in May 2017, it is recommended that women who have not had sex in 9-14 years of age are the main target group, and women over the age of 15 are secondary target groups.
How many times does the vaccine need to be inoculated
Bivalent, tetravalent, and pentavalent vaccines require three injections and are completed within six months.
Among them, the bivalent vaccine is recommended to be inoculated in 0, 1, and 6 months, and a total of 3 doses. The second dose can be inoculated between 1 and 2.5 months after the first dose, and the third dose can be completed 5-12 months after the first dose.
The four-valent and nine-valent vaccines are recommended to be inoculated in 0, 2, and 6 months, and a total of 3 doses are given. The first agent and the second agent are separated by at least one month, and the second agent and the third agent are separated by at least three months, and all three doses should be completed within one year.
Is it still useful for married women who have been vaccinated?
Some of the married women have not been infected with the virus, or have not been infected with the HPV subtype contained in the vaccine. At this time, vaccination is also effective.
Can men be vaccinated?
At present, all vaccines approved in China are used by women to prevent cervical cancer.
In foreign countries, tetravalent vaccines approved by some countries can be used for male vaccination. Male vaccination can also prevent precancerous lesions of some reproductive organs, wetness and so on.
In addition, male vaccination is conducive to the emergence of group immune effects, resulting in a decrease in the overall infection rate of HPV virus in the population.
What are the side effects of the vaccine?
The safety of the vaccine is still very good. The same kind of adverse reactions are mainly headache, fever, nausea, dizziness, etc., and the local adverse reactions are mainly pain, swelling, erythema, itching and the like.
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