The use of bottle-planting apples will start the bottle-holding process from the young fruit period. The entire growth period and the picking, transportation, storage, etc. are in the bottle, there is no pesticide pollution and secondary pollution, in line with the requirements of pollution-free production; Large temperature difference between day and night, is conducive to the accumulation of sugar; sets of fruit high pile, and the size, shape, color, etc. exactly the same as the factory processing, than the red star fruit shape is even more beautiful. At room temperature, the set of fruit can be put into three or four months of the following year, which is much longer than the storage period of ordinary apples. If processed and matched with green leaves and safflowers, the apple is crystal clear and beautiful. Apple's bottle is a long round, weighing about 60 grams, a diameter of about 10 cm, 2 cm high mouth, bottle diameter is very small, only stuffed into the thumb. Leave two small holes under the bottle as ventilation holes. Apple's bottle-holding technology is stricter than ordinary bagging technology. The following points must be noted in the management: 1 Accurate selection. The fruit set in the bottle should be selected, and the fruit shape on the long fruit branch should be longer. 2 timely fruit thinning. In the late April, thinning the fruit, the distance between the fruit and the fruit should be about 30 centimeters, to prevent collision caused by the wind, resulting in damage to the bottle. 3 timely bottle sets. Bottles are generally in early May, 10 to 15 days earlier than bagging, and then 15 to 20 days after bottled. Then the paper bag is set, because the fruit of the bottle is protected and the light grows faster. 4 use fruit shape agent. The fruit shape index of the set of bottle fruit is large. The fruit form must be sprayed to strengthen the longitudinal growth of the apple. Generally, it is sprayed once in the flowering period and one week after the flowering. 5 sets of bottles fixed. The plastic bottle can be used to fix the bottle on the branches of the fruit. 6 timely bag to harvest. Sets of bottle fruit should be carefully managed with fruit as a unit, observed at any time, timely bag removal, after the general fruit red, they can pick. 7 processing seals. After picking, the bottle mouth is sealed with plastic and the vent hole at the bottom of the bottle is sealed with wax. After such treatment, Apple's freshness can be greatly extended.
Pharmaceutical intermediates
Drug Intermediates -Pharmaceutical intermediates: A material that is produced during a process step of the drug substance and must undergo further molecular changes or refining before it becomes a drug substance. The intermediates can be separated or not separated.
Active Pharmaceutical Ingredient (APIS)(or Drug Substance) : Active Pharmaceutical Ingredient (API)(or Drug Substance) : Any substance or mixture of substances intended to be used in the manufacture of pharmaceutical products and, when used in pharmaceutical products, to be an active ingredient in pharmaceutical products. Such substances have pharmacological activity or other direct effects in the diagnosis, treatment, symptom relief, management or prevention of disease, or can affect the function and structure of the body. As can be seen from the definition, the Intermediates APIS is a key product of the previous process of manufacturing the API and has a different structure from the API
Finally, for example, amoxicillin capsules are called preparations, amoxicillin is called APIS, and 6-APA is called Veterinary Intermediates APIS.
Penicillin potassium for injection is called preparation, penicillin potassium is called Veterinary raw materials, and green potassium industrial salt is called intermediate
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